Nucleotide sequence of the ospAB operon of a Borrelia burgdorferi strain expressing OspA but not OspB-Reference-Cited by-同舟云学术

Nucleotide sequence of the ospAB operon of a Borrelia burgdorferi strain expressing OspA but not OspB

Published:1992-05 Issue:5 Volume:60 Page:1864-1868
ISSN:0019-9567
Container-title:Infection and Immunity
language:en
Short-container-title:Infect Immun

Author:

Eiffert H¹,Ohlenbusch A¹,Fehling W¹,Lotter H¹,Thomssen R¹

Affiliation:

1. Department of Medical Microbiology, University of Göttingen, Germany.

Abstract

The nucleotide sequence of a 1.6-kb clone containing the gene for outer surface protein A (OspA) of a German strain (GO2) of Borrelia burgdorferi was determined. The deduced amino acid sequence showed a homology of 82% to the OspA molecules from three other B. burgdorferi strains. The best-conserved region was recognized at the 36-amino-terminal amino acids of OspA. OspB could not be identified in the strain investigated, probably because the nucleotide sequence of the ospAB operon prevented expression of the OspB gene.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

Link

https://journals.asm.org/doi/pdf/10.1128/iai.60.5.1864-1868.1992

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