Affiliation:
1. Faculty of Pharmaceutical Sciences, Chiba University, Inage-ku, Chiba 263-8522, Japan
Abstract
ABSTRACT
Enterococcus hirae
ATCC 9790 grew well in Na
+
-deficient, low-K
+
medium, but growth was inhibited by carbonylcyanide
m
-chlorophenylhydrazone (CCCP). Growth inhibition and decrease of cellular K
+
levels in the presence of CCCP were relieved by the addition of Na
+
and a high concentration of K
+
. In contrast, in the mutant defective in Na
+
-ATPase or the NtpJ component of the KtrII K
+
uptake system, CCCP-induced growth inhibition was rescued by a high concentration of K
+
but not of Na
+
. These transporters are thus indispensable for homeostatis of K
+
and Na
+
at low proton potential.
Publisher
American Society for Microbiology
Subject
Molecular Biology,Microbiology
Reference22 articles.
1. Increased membrane ATPase and K+ transport rates in Streptococcus faecalis induced by K+ restriction during growth;Abrams A.;Biochem. Biophys. Res. Commun.,1971
2. Bakker
E. P.
Alkali cation transport systems in prokaryotes.
1993
CRC Press
Boca Raton Fla
3. Energy coupling to potassium transport in Streptococcus faecalis: interplay of ATP and the protonmotive force;Bakker E. P.;J. Biol. Chem.,1980
4. Genus Streptococcus;Hardie J. M.;Bergey’s manual of systematic bacteriology,1986
5. Ion currents and physiological functions in microorganisms;Harold F. M.;Annu. Rev. Microbiol.,1977
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