A Subinhibitory Concentration of Clarithromycin Inhibits Mycobacterium avium Biofilm Formation-Reference-Cited by-同舟云学术

A Subinhibitory Concentration of Clarithromycin Inhibits Mycobacterium avium Biofilm Formation

Published:2004-12 Issue:12 Volume:48 Page:4907-4910
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Carter George¹,Young Lowell S.¹,Bermudez Luiz E.¹²

Affiliation:

1. Kuzell Institute, California Pacific Medical Center Research Institute, San Francisco, California

2. Department of Biomedical Sciences, College of Veterinary Medicine, and Department of Microbiology, College of Science, Oregon State University, Corvallis, Oregon

Abstract

ABSTRACT Mycobacterium avium causes disseminated infection in immunosuppressed individuals and lung infection in patients with chronic lung diseases. M. avium forms biofilm in the environment and possibly in human airways. Antibiotics with activity against the bacterium could inhibit biofilm formation. Clarithromycin inhibits biofilm formation but has no activity against established biofilm.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.48.12.4907-4910.2004

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