Community-Onset Disease Caused by Citrobacter freundii Producing a Novel CTX-M β-Lactamase, CTX-M-30, in Canada-Reference-Cited by-同舟云学术

Community-Onset Disease Caused by Citrobacter freundii Producing a Novel CTX-M β-Lactamase, CTX-M-30, in Canada

Published:2004-11 Issue:11 Volume:48 Page:4435-4437
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Abdalhamid Baha¹,Pitout Johann D. D.²,Moland Ellen S.¹,Hanson Nancy D.¹

Affiliation:

1. Department of Medical Microbiology and Immunology, Center for Research in Antiinfectives & Biotechnology, Creighton University School of Medicine, Omaha, Nebraska

2. Division of Microbiology, Calgary Laboratory Services, and Department of Pathology & Laboratory Medicine, University of Calgary, Calgary, Alberta, Canada

Abstract

ABSTRACT Strains of Citrobacter freundii intermediate to cefotaxime but sensitive to ceftazidime were isolated from four different patients in Canada. Sequencing of PCR products by use of CTX-M-specific primers revealed a new combination of four amino acid substitutions. This new gene was designated bla CTX-M-30 and was encoded on a 3-kb plasmid. The pI of CTX-M-30 was 8.0.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.48.11.4435-4437.2004

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