Author:
Imaeda T,Kirchheimer W F,Barksdale L
Abstract
DNA derived from Mycobacterium leprae (grown in armadillos) was isolated, purified, and analyzed spectrophotometrically. The genome size and the guanine-plus-cytosine content of M. leprae were 1.3 x 10(9) and 55.8%, respectively. Among selected strains of mycobacterial, nocardial, and corynebacterial species, Corynebacterium sp. 2628 LB, isolated from a human leprosy patient, showed the highest DNA homology with M. leprae. Of the DNAs derived from mycobacteria, those of M. tuberculosis and M. scrofulaceum showed a comparatively high reassociation with the DNMA of M. liprae.
Publisher
American Society for Microbiology
Subject
Molecular Biology,Microbiology
Reference32 articles.
1. Constituants lipidiques de Mycobacterium leprae isole de tatou infecte experimentalement;Amselineau C.;Ann. Inst. Pasteur (Paris),1981
2. Deoxyribonucleic acid hybridization between different species of mycobacteria;Baess I.;Acta Pathol. Microbiol. Scand.,1978
3. Chemical characterization of organisms isolated from leprosy patients;Beaman B. L.;J. Bacteriol.,1974
4. Comparison of various preparations of Mycobacterium leprae and other mycobacteria by Iymphocyte stimulation;Bjune G.;Int. J. Lepr.,1978
5. Relationships among mycobacteria and nocardiae based upon deoxyribonucleic acid reassociation;Bradley S. G.;J. Bacteriol.,1973
Cited by
47 articles.
订阅此论文施引文献
订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献