Pooled Saliva Specimens for SARS-CoV-2 Testing-Reference-Cited by-同舟云学术

Pooled Saliva Specimens for SARS-CoV-2 Testing

Published:2021-02-18 Issue:3 Volume:59 Page:
ISSN:0095-1137
Container-title:Journal of Clinical Microbiology
language:en
Short-container-title:J Clin Microbiol

Author:

Barat Bidisha¹,Das Sanchita¹,De Giorgi Valeria²,Henderson David K.³,Kopka Stacy⁴,Lau Anna F.¹,Miller Tracey⁴,Moriarty Theresa⁵,Palmore Tara N.³,Sawney Shari⁵,Spalding Chris³,Tanjutco Patricia⁵,Wortmann Glenn⁵,Zelazny Adrian M.¹,Frank Karen M.¹^ORCID

Affiliation:

1. Department of Laboratory Medicine, National Institutes of Health, Bethesda, Maryland, USA

2. Department of Transfusion Medicine, National Institutes of Health, Bethesda, Maryland, USA

3. Hospital Epidemiology Service, Clinical Center, National Institutes of Health, Bethesda, Maryland, USA

4. Clinical Monitoring Research Program Directorate, Frederick National Laboratory for Cancer Research, Rockville, Maryland, USA

5. MedStar Washington Hospital Center, Washington, DC, USA

Abstract

We evaluated saliva (SAL) specimens for SARS-CoV-2 reverse transcriptase PCR (RT-PCR) testing by comparison of 459 prospectively paired nasopharyngeal (NP) or midturbinate (MT) swabs from 449 individuals with the aim of using saliva for asymptomatic screening. Samples were collected in a drive-through car line for symptomatic individuals ( n = 380) and in the emergency department (ED) ( n = 69).

Funder

NIH Intramural Research Funding

HHS | NIH | National Cancer Institute

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Link

https://journals.asm.org/doi/pdf/10.1128/JCM.02486-20

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