Ring Finger Protein 34 Facilitates Nervous Necrosis Virus Evasion of Antiviral Innate Immunity by Targeting TBK1 and IRF3 for Ubiquitination and Degradation in Teleost Fish-Reference-Cited by-同舟云学术

Ring Finger Protein 34 Facilitates Nervous Necrosis Virus Evasion of Antiviral Innate Immunity by Targeting TBK1 and IRF3 for Ubiquitination and Degradation in Teleost Fish

Published:2023-06-29 Issue:6 Volume:97 Page:
ISSN:0022-538X
Container-title:Journal of Virology
language:en
Short-container-title:J Virol

Author:

Zhang Wanwan¹²³⁴,Yao Lan¹²³⁴,Chen Leshi¹²³⁴,Jia Peng¹⁵,Xiang Yangxi¹⁶,Yi Meisheng¹²³⁴,Jia Kuntong¹²³⁴^ORCID

Affiliation:

1. School of Marine Sciences, Sun Yat-sen University, Guangzhou, China

2. Guangdong Provincial Key Laboratory of Marine Resources and Coastal Engineering, Guangzhou, China

3. Pearl River Estuary Marine Ecosystem Research Station, Ministry of Education, Zhuhai, China

4. Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai), Zhuhai, China

5. Fuzhou Medical University, Fuzhou, Jiangxi, China

6. State Key Laboratory for Quality and Safety of Agro-products, Ningbo University, Ningbo, China

Abstract

Ubiquitination plays an essential role in the regulation of innate immune responses to pathogens. NNV, a type of RNA virus, is the causal agent of a highly destructive disease in a variety of marine and freshwater fish.

Funder

MOST | National Natural Science Foundation of China

China Postdoctoral Science Foundation | Postdoctoral Research Foundation of China

Natural Science Foundation of Guangxi Province

Natural Science Foundation of Guangdong Province

Education Department of Jiangxi Province

Zhuhai Social Development Field Science and Technology Planning Project

Scientific and Technological Planning Project of Guangzhou City

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology