Zebrafish MAP2K7 Simultaneously Enhances Host IRF7 Stability and Degrades Spring Viremia of Carp Virus P Protein via Ubiquitination Pathway-Reference-Cited by-同舟云学术

Zebrafish MAP2K7 Simultaneously Enhances Host IRF7 Stability and Degrades Spring Viremia of Carp Virus P Protein via Ubiquitination Pathway

Published:2023-07-27 Issue:7 Volume:97 Page:
ISSN:0022-538X
Container-title:Journal of Virology
language:en
Short-container-title:J Virol

Author:

Zhang Can¹²,Lu Long-Feng¹,Li Zhuo-Cong¹²,Han Ke-Jia¹³,Wang Xue-Li¹³,Chen Dan-Dan¹,Xiong Feng¹,Li Xi-Yin¹⁴,Zhou Li¹⁴,Ge Feng¹^ORCID,Li Shun¹

Affiliation:

1. Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan, China

2. University of Chinese Academy of Sciences, Beijing, China

3. College of Fisheries and Life Science, Dalian Ocean University, Dalian, China

4. State Key Laboratory of Freshwater Ecology and Biotechnology, Hubei Hongshan Laboratory, The Innovative Academy of Seed Design, Chinese Academy of Sciences, Wuhan, China

Abstract

Normally, during viral infection, host antiviral factors individually modulate the host immune response or antagonize viral components to defense infection. In the present study, we report that zebrafish MAP2K7 plays a crucial positive role in the host antiviral process.

Funder

MOST | National Natural Science Foundation of China

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/jvi.00532-23

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