A Small Molecule Coordinates Symbiotic Behaviors in a Host Organ-Reference-Cited by-同舟云学术

A Small Molecule Coordinates Symbiotic Behaviors in a Host Organ

Published:2021-04-27 Issue:2 Volume:12 Page:
ISSN:2150-7511
Container-title:mBio
language:en
Short-container-title:mBio

Author:

Zink Katherine E.¹,Ludvik Denise A.²³^ORCID,Lazzara Phillip R.¹,Moore Terry W.¹⁴,Mandel Mark J.²^ORCID,Sanchez Laura M.¹⁵^ORCID

Affiliation:

1. Department of Pharmaceutical Sciences, University of Illinois at Chicago, Chicago, Illinois, USA

2. Department of Medical Microbiology and Immunology, University of Wisconsin-Madison, Madison, Wisconsin, USA

3. Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA

4. University of Illinois Cancer Center, University of Illinois at Chicago, Chicago, Illinois, USA

5. Department of Chemistry & Biochemistry, University of California, Santa Cruz, California, USA

Abstract

The complexity of animal microbiomes presents challenges to defining signaling molecules within the microbial consortium and between the microbes and the host. By focusing on the binary symbiosis between Vibrio fischeri and Euprymna scolopes , we have combined genetic analysis with direct imaging to define and study small molecules in the intact symbiosis.

Funder

HHS | National Institutes of Health

Publisher

American Society for Microbiology

Subject

Virology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/mBio.03637-20

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