Performance Characteristics of an Enzyme-Linked Immunosorbent Assay for Determining Salivary Immunoglobulin G Response to Helicobacter pylori-Reference-Cited by-同舟云学术

Performance Characteristics of an Enzyme-Linked Immunosorbent Assay for Determining Salivary Immunoglobulin G Response to Helicobacter pylori

Published:1999-02 Issue:2 Volume:37 Page:430-432
ISSN:0095-1137
Container-title:Journal of Clinical Microbiology
language:en
Short-container-title:J Clin Microbiol

Author:

De Pascalis R.¹,Del Pezzo M.¹,Nardone G.²,Budillon G.²,Lavitola A.¹

Affiliation:

1. Cattedra di Microbiologia Clinica, Dipartimento di Biologia e Patologia Cellulare e Molecolare,1 and

2. Cattedra di Gastroenterologia, Dipartimento di Patologia Sistematica,2 Universita’ degli Studi di Napoli “Federico II,” 80131 Naples, Italy

Abstract

ABSTRACT We evaluated the salivary immunoglobulin G (IgG) immune response to Helicobacter pylori in 70 subjects by enzyme-linked immunosorbent assay (ELISA). Subjects with a positive H. pylori culture showed significantly higher titers of antibodies than subjects with no detectable H. pylori : the overall sensitivity and specificity of the test were 84 and 90%, respectively. The detection of salivary anti- H. pylori IgG antibodies may be considered as an alternative to serum IgG detection for ease of sample collection or when blood samples are not available in screening of patients with dyspepsia.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Link

https://journals.asm.org/doi/pdf/10.1128/JCM.37.2.430-432.1999

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