In Vitro Adhesion and Platelet Aggregation Properties of Bacteremia-Associated Lactobacilli

Author:

Kirjavainen Pirkka V.1,Tuomola Elina M.1,Crittenden Ross G.2,Ouwehand Arthur C.1,Harty Derek W. S.3,Morris Leone F.2,Rautelin Hilpi4,Playne Martin J.2,Donohue Diana C.5,Salminen Seppo J.15

Affiliation:

1. Department of Biochemistry and Food Chemistry, University of Turku, Turku,1 and

2. Food Science Australia2 and

3. Institute of Dental Research, Faculty of Dentistry, University of Sydney, Sydney,3 Australia

4. Department of Bacteriology and Immunology, University of Helsinki, Helsinki,4 Finland, and

5. Key Centre for Applied and Nutritional Toxicology, Royal Melbourne Institute of Technology,5 Melbourne, and

Abstract

ABSTRACT Eight bacteremia-associated Lactobacillus strains were evaluated in vitro for the ability to adhere to human intestinal mucosa and to aggregate platelets. Adherence varied significantly among the strains, and platelet aggregation was induced by three strains. In conclusion, strong binding ability does not appear to be a prerequisite for the involvement of lactobacilli in bacteremia or to their ability to aggregate platelets.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

Reference15 articles.

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2. Brassart D. Neeser J.-R. Michetti P. Servin A. L. The selection of dairy bacterial strains with probiotic properties based on their adhesion to human intestinal epithelial cells Actes du Colloque Lactic 94. 1995 201 212 Presse Universitaires de Caen Caen France

3. Felten A. Barreau C. Tailliez P. Bizet C. Philippon A. Phenotypic and genotypic relationship between Lactobacillus rhamnosus clinical isolates from immunocompromised patients abstr. 084 Final programme and book of abstracts of the XXIst International Congress on Microbial Ecology and Disease. 1996 60 Society for Microbial Ecology and Disease Paris France

4. Common themes in microbial pathogenicity revisited

5. The aggregation of human platelets by Lactobacillus species;Harty D. W. S.;J. Gen. Microbiol.,1993

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