Isolation and Characterization of the Saccharomyces cerevisiae XPT1 Gene Encoding Xanthine Phosphoribosyl Transferase-Reference-Cited by-同舟云学术

Isolation and Characterization of the Saccharomyces cerevisiae XPT1 Gene Encoding Xanthine Phosphoribosyl Transferase

Published:1999-05 Issue:9 Volume:181 Page:2984-2986
ISSN:0021-9193
Container-title:Journal of Bacteriology
language:en
Short-container-title:J Bacteriol

Author:

Guetsova M. L.¹,Crother T. R.²,Taylor M. W.²,Daignan-Fornier B.¹

Affiliation:

1. Institut de Biochimie et Génétique Cellulaires, CNRS UPR9026, F-33077 Bordeaux Cedex, France,1 and

2. Department of Biology, Indiana University, Bloomington, Indiana 474052

Abstract

ABSTRACT A new Saccharomyces cerevisiae gene, XPT1 , was isolated as a multicopy suppressor of a hypoxanthine phosphoribosyl transferase (HPRT) defect. Disruption of XPT1 affects xanthine utilization in vivo and results in a severe reduction of xanthine phosphoribosyl transferase (XPRT) activity while HPRT is unaffected. We conclude that XPT1 encodes XPRT in yeast.

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/JB.181.9.2984-2986.1999

Reference14 articles.

1. APT1 , but Not APT2 , Codes for a Functional Adenine Phosphoribosyltransferase in Saccharomyces cerevisiae

2. Cloning and characterization of the adenine phosphoribosyltransferase-encoding gene (APT1) from Saccharomyces cerevisiae;Alfonzo J. D.;Gene,1995

3. MBR1 and MBR3, two related yeast genes that can suppress the growth defect of hap2, hap3 and hap4 mutants;Daignan-Fornier B.;Mol. Gen. Genet.,1994

4. Strategy for deletion of complete open reading frames in Saccharomyces cerevisiae;Eberhardt I.;Curr. Genet.,1995

5. New yeast-Escherichia coli shuttle vectors constructed with in vitro mutagenized yeast genes lacking six-base pair restriction sites;Gietz R. D.;Gene,1988

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