Peripheral Nerve Injury Induced by Japanese Encephalitis Virus in C57BL/6 Mouse

Author:

Yang Huan1,Wang Xiaoli2,Wang Zhao3,Wang Guowei4,Fu Shihong56,Li Fan56,Yang Liping4,Yuan Yanping4,Shen Kaichun4,Wang Huanyu56,Wang Zhenhai789ORCID

Affiliation:

1. General Hospital of Ningxia Medical University, Yinchuan, China

2. The No. 1 People’s Hospital of Shizuishan, Shizuishan, China

3. The Second Affiliated Hospital of Air Force Medical University, Xi'an, China

4. Ningxia Medical University, Yinchuan, China

5. Department of Viral Encephalitis, NHC Key Laboratory of Biosafety, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China

6. State Key Laboratory for Infectious Disease Prevention and Control, Chinese Center for Disease Control and Prevention, Beijing, China

7. Institute of Medical Sciences, General Hospital of Ningxia Medical University, Yinchuan, China

8. Diagnosis and Treatment Engineering Technology Research Center of Nervous System Diseases of Ningxia Hui Autonomous Region, Yinchuan, China

9. Neurology Center, General Hospital of Ningxia Medical University, Yinchuan, China

Abstract

JEV is a neurotropic flavivirus belonging to the Flaviviridae family and causes high mortality and disability rates. It invades the central nervous system and induces acute inflammatory injury and neuronal death.

Funder

National Natural Science Foundation of China

宁夏回族自治区科学技术厅 | Key Research and Development Program of Ningxia

CCDC | State Key Laboratory of Infectious Disease Prevention and Control

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

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