Pathogenesis of Wild-Type-Like Rhesus Cytomegalovirus Strains following Oral Exposure of Immune-Competent Rhesus Macaques-Reference-Cited by-同舟云学术

Pathogenesis of Wild-Type-Like Rhesus Cytomegalovirus Strains following Oral Exposure of Immune-Competent Rhesus Macaques

Published:2022-02-09 Issue:3 Volume:96 Page:
ISSN:0022-538X
Container-title:Journal of Virology
language:en
Short-container-title:J Virol

Author:

Yue Yujuan¹,Chang W. L. William¹,Li Julia²,Nguyen Nancy¹,Schmidt Kimberli A.¹,Dormitzer Philip R.²,Yang Xinzhen²,Barry Peter A.¹³⁴^ORCID

Affiliation:

1. Center for Immunology and Infectious Diseases, University of California, Davis, California, USA

2. Vaccine Research and Development, Pfizer, Inc., Pearl River, New York, USA

3. Department of Pathology and Laboratory Medicine, University of California, Davis, California, USA

4. California National Primate Research Center, University of California, Davis, California, USA

Abstract

Human cytomegalovirus (HCMV) is globally ubiquitous with high seroprevalence rates in all communities. HCMV infections can occur vertically following mother-to-fetus transmission across the placenta and horizontally following shedding of virus in bodily fluids in HCMV-infected hosts and subsequent exposure of susceptible individuals to virus-laden fluids.

Funder

Pfizer

HHS | National Institutes of Health

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/jvi.01653-21

Reference112 articles.

1. Estimation of the worldwide seroprevalence of cytomegalovirus: A systematic review and meta-analysis

2. Investigation of CMV disease in immunocompromised patients