Peroxisomal localization and activation by bivalent metal ions of ureidoglycolate lyase, the enzyme involved in urate degradation in Candida tropicalis

Author:

Takada Y,Tsukiji N

Abstract

Ureiodoglycolate lyase (EC 4.3.2.3) was found only in the peroxisomes in urate-induced Candida tropicalis. The enzyme was markedly activated by the bivalent metal ions Mn2+, Fe2+, and Ni2+. The activation by Mn2+ was suggested to be the result of its binding to the apoenzyme.

Publisher

American Society for Microbiology

Subject

Molecular Biology,Microbiology

Reference14 articles.

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