Clonal Dissemination and mupA Gene Polymorphism of Mupirocin-Resistant Staphylococcus aureus Isolates from Long-Term-Care Facilities in South Korea-Reference-Cited by-同舟云学术

Clonal Dissemination and mupA Gene Polymorphism of Mupirocin-Resistant Staphylococcus aureus Isolates from Long-Term-Care Facilities in South Korea

Published:2006-01 Issue:1 Volume:50 Page:365-367
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Yoo Jae Il¹,Shin Eun Shim¹,Cha Jeong Ok¹,Lee Jeom Kyu¹,Jung Young Hee,Lee Kyeong Min¹,Kim Bong Su¹,Lee Yeong Seon¹

Affiliation:

1. Laboratory of Antimicrobial Resistant Pathogens, Department of Microbiology, National Institute of Health, KCDC, Seoul, South Korea

Abstract

ABSTRACT We identified 25 high-level mupirocin-resistant (MuH) and 21 low-level mupirocin-resistant (MuL) Staphylococcus aureus isolates from eight long-term-care facilities (LTCFs). The pulsed-field gel electrophoresis patterns of 19 MuH and 19 MuL isolates from two facilities were identical for 18 and 15 isolates, respectively. The most predominant mupA restriction fragment length polymorphism type was found in 21 MuH isolates. We conclude that clonal transmission of MuH and MuL S. aureus strains occurred in these LTCFs. This is the first report of clonal transfer of mupirocin resistance in LTCFs.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.50.1.365-367.2006

Reference23 articles.

1. Bonomo, R. A. 2000. Multiple antibiotic-resistant bacteria in long-term care facilities: an emerging problem in the practice of infectious diseases. Clin. Infect. Dis.31:1414-1422.

2. Bradley, S. F. 1999. Methicillin-resistant Staphylococcus aureus: long-term care concerns. Am. J. Med.106:2S-10S.

3. Cederna, J. E., M. S. Terpenning, M. Ensberg, S. F. Bradley, and C. A. Kauffman. 1990. Staphylococcus aureus nasal colonization in a nursing home: eradication with mupirocin. Infect. Control Hosp. Epidemiol.11:13-16.

4. Connolly, S., W. C. Noble, and I. Phillips. 1993. Mupirocin resistance in coagulase-negative staphylococci. J. Med. Microbiol.39:450-453.

5. Cookson, B. D., R. W. Lacey, W. C. Noble, D. S. Reeves, R. Wise, and R. J. Redhead. 1990. Mupirocin-resistant Staphylococcus aureus. Lancet335:1095-1096.

Cited by 17 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Distribution of high-level mupirocin resistance among clinical MRSA;Journal of Chemotherapy;2016-07-04

2. Antimicrobial resistance ofStaphylococcus aureusisolated from skin infections and its implications in various clinical conditions in Korea;International Journal of Dermatology;2016-02-19

3. Preventing meticillin-sensitive Staphylococcus aureus bacteriemia in children;Journal of Pediatric Infectious Diseases;2015-07-28

4. In VitroAntimicrobial Activities of Fusidic Acid and Retapamulin against Mupirocin- and Methicillin-ResistantStaphylococcus aureus;Annals of Dermatology;2015

5. Fitness Costs of Antibiotic Resistance;Antibiotics;2013-10-04