Two Polyketides Intertwined in Complex Regulation: Posttranscriptional CsrA-Mediated Control of Colibactin and Yersiniabactin Synthesis in Escherichia coli-Reference-Cited by-同舟云学术

Two Polyketides Intertwined in Complex Regulation: Posttranscriptional CsrA-Mediated Control of Colibactin and Yersiniabactin Synthesis in Escherichia coli

Published:2022-02-22 Issue:1 Volume:13 Page:
ISSN:2150-7511
Container-title:mBio
language:en
Short-container-title:mBio

Author:

Rehm Nadine¹²,Wallenstein Alexander¹,Keizers Marla¹,Homburg Stefan³,Magistro Giuseppe⁴,Chagneau Camille V.⁵^ORCID,Klimek Hanna¹,Revelles Olga⁶,Helloin Emmanuelle⁵⁷,Putze Johannes¹³,Nougayrède Jean-Philippe⁵^ORCID,Schubert Sören⁸,Oswald Eric⁵^ORCID,Dobrindt Ulrich¹²³^ORCID

Affiliation:

1. Institut für Hygiene, Universität Münster, Münster, Germany

2. Interdisziplinäres Zentrum für Klinische Forschung (IZKF) Münster, Universität Münster, Münster, Germany

3. Institut für Molekulare Infektionsbiologie, Universität Würzburg, Würzburg, Germany

4. Urologische Klinik und Poliklinik, Ludwig-Maximilians-Universität München, Munich, Germany

5. IRSD, Université de Toulouse, INSERM, INRA, ENVT, UPS, Toulouse, France

6. LISBP, Université de Toulouse, CNRS, INRA, INSA, UPS, Toulouse, France

7. ISP, INRA, Université de Tours, UMR 1282, Nouzilly, France

8. Max von Pettenkofer-Institut für Hygiene und Medizinische Mikrobiologie, Medizinische Fakultät, Ludwig-Maximilians-Universität München, Munich, Germany

Abstract

Secondary metabolite expression is a widespread strategy among bacteria to improve their fitness in habitats where they constantly compete for resources with other bacteria. The production of secondary metabolites is associated with a metabolic and energetic burden.

Funder

Interdisciplinary Center for Clinical Research Münster

Agence Nationale de la Recherche

Deutsche Forschungsgemeinschaft

Publisher

American Society for Microbiology

Subject

Virology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/mbio.03814-21

Reference99 articles.

1. Genetic Structure and Distribution of the Colibactin Genomic Island among Members of the Family Enterobacteriaceae