Repression of Memo1, a Novel Target of Human Papillomavirus Type 16 E7, Increases Cell Proliferation in Cervical Cancer Cells-Reference-Cited by-同舟云学术

Repression of Memo1, a Novel Target of Human Papillomavirus Type 16 E7, Increases Cell Proliferation in Cervical Cancer Cells

Published:2022-10-26 Issue:20 Volume:96 Page:
ISSN:0022-538X
Container-title:Journal of Virology
language:en
Short-container-title:J Virol

Author:

Trejo-Cerro Oscar¹,Massimi Paola¹,Broniarczyk Justyna¹²,Myers Michael¹,Banks Lawrence¹^ORCID

Affiliation:

1. International Centre for Genetic Engineering and Biotechnology, Trieste, Italy

2. Department of Molecular Virology, Adam Mickiewicz University, Poznan, Poland

Abstract

Although numerous targets have been reported to interact with the HPV E7 oncoprotein, the mechanisms involved in HPV-induced carcinogenesis and the maintenance of cell transformation are still lacking. Here, through pulldown assays using a peptide encompassing the C-terminal region of HPV16 E7, we report Memo1 as a novel E7 interactor.

Funder

Associazione Italiana per la Ricerca sul Cancro

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/jvi.01229-22

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