Affiliation:
1. Southeastern Fruit and Tree Nut Research Station, U.S. Department of Agriculture, Byron, Georgia 31008, and National Peanut Research Laboratory, U.S. Department of Agriculture, Dawson, Georgia 31742
Abstract
A diarrheagenic toxin from culture extracts of
Aspergillus wentii
Wehmer isolated from weevil-damaged Chinese chestnuts was identified as emodin (2-methyl-4,5,7-trihydroxyanthraquinone). The orange-red, crystalline toxin (mp 255 to 257 C) showed ultraviolet absorption maxima in ethyl alcohol at 223, 250, 267, 290, and 442 nm, and infrared absorption maxima at 3,400 cm
-1
(OH), 1,635, and 1,625 cm
-1
. Chemical shifts and coupling constants of the proton magnetic resonance spectra of the
A. wentii
toxin and of authentic emodin agreed. Mean lethal dose of emodin orally administered to 1 day old DeKalb cockerels was 3.7 mg/kg.
Publisher
American Society for Microbiology
Subject
General Pharmacology, Toxicology and Pharmaceutics,General Immunology and Microbiology,General Biochemistry, Genetics and Molecular Biology,General Medicine
Cited by
27 articles.
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