Affiliation:
1. Infectious Disease Research Centre, Laval University, Quebec City, Quebec, Canada
Abstract
ABSTRACT
Evaluation of candidate antiviral drugs against Epstein-Barr virus (EBV), human herpesvirus 6 (HHV-6), and HHV-8 is hampered by the lack of convenient laboratory assays. We developed real-time quantitative PCR assays performed on supernatants of lymphoma cell lines and determined the 50% inhibitory concentrations (IC
50
s) of nucleoside, nucleotide, and pyrophosphate analogues against these herpesviruses.
Publisher
American Society for Microbiology
Cited by
14 articles.
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