Direct Detection of Carbapenemase-Producing Klebsiella pneumoniae by MALDI-TOF Analysis of Full Spectra Applying Machine Learning-Reference-Cited by-同舟云学术

Direct Detection of Carbapenemase-Producing Klebsiella pneumoniae by MALDI-TOF Analysis of Full Spectra Applying Machine Learning

Published:2023-06-20 Issue:6 Volume:61 Page:
ISSN:0095-1137
Container-title:Journal of Clinical Microbiology
language:en
Short-container-title:J Clin Microbiol

Author:

Gato Eva¹,Arroyo Manuel J.²,Méndez Gema²,Candela Ana¹,Rodiño-Janeiro Bruno Kotska¹,Fernández Javier³^ORCID,Rodríguez-Sánchez Belén⁴,Mancera Luis²,Arca-Suárez Jorge¹⁵,Beceiro Alejandro¹⁵^ORCID,Bou Germán¹⁵,Oviaño Marina¹⁵^ORCID

Affiliation:

1. Servicio de Microbiología, Complejo Hospitalario Universitario A Coruña, A Coruña, Spain

2. Clover Bioanalytical Software S.L., Granada, Spain

3. Servicio de Microbiología, Hospital Central de Asturias, Oviedo, Spain

4. Servicio de Microbiología, Hospital General Gregorio Marañón, Madrid, Spain

5. Centro de Investigación Biomedica en Red Enfermedades Infecciosas (CIBERINFEC). Instituto de Salud Carlos III (ISCIII), Madrid, Spain

Abstract

MALDI-TOF MS is considered to be an important tool for the future development of rapid microbiological techniques. We propose the application of MALDI-TOF MS as a dual technique for the identification of bacteria and the detection of resistance, with no extra hands-on procedures.

Funder

Sociedad Española de Enfermedades Infecciosas y Microbiología Clínica

MEC | Instituto de Salud Carlos III

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Link

https://journals.asm.org/doi/pdf/10.1128/jcm.01751-22

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