DNA Sequence Variation within vanA , vanB , vanC-1 , and vanC-2/3 Genes of Clinical Enterococcus Isolates-Reference-Cited by-同舟云学术

DNA Sequence Variation within vanA , vanB , vanC-1 , and vanC-2/3 Genes of Clinical Enterococcus Isolates

Published:1998-01 Issue:1 Volume:42 Page:202-205
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Patel Robin¹,Uhl Jim R.¹,Kohner Peggy¹,Hopkins Marlene K.¹,Steckelberg James M.¹,Kline Bruce¹,Cockerill Franklin R.¹

Affiliation:

1. Divisions of Clinical Microbiology and Molecular Biology, Mayo Clinic and Foundation, Rochester, Minnesota

Abstract

ABSTRACT We studied the DNA sequence variation of van genes of 34 isolates of Enterococcus spp. The isolates containing the vanB gene exhibited between 0 and 41 base pair changes per 801 bp studied when the vanB sequences were compared to that of the reference strain Enterococcus faecalis V583. The isolates carrying the vanC-2 gene exhibited between 0 and 23 base pair changes per 346 bp studied when the vanC-2 sequences were compared to that of the reference strain E. casseliflavus ATCC 25788. Little variation was noted in the vanA and vanC-1 genes.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.42.1.202

Reference7 articles.

1. Sequence of the vanB and ddl genes encoding d-alanine:d-lactate and d-alanine:d-alanine ligases in vancomycin-resistant Enterococcus faecalis V583;Evers S.;Gene,1994

2. The vanB gene of vancomycin-resistant Enterococcus faecalis V583 is structurally related to genes encoding d-Ala:d-Ala ligases and glycopeptide-resistance proteins VanA and VanC;Evers S.;Gene,1993

3. A gene conferring resistance to vancomycin but not teicoplanin in isolates of Enterococcus faecalis and Enterococcus faecium demonstrates homology with vanB, vanA, and vanC genes of enterococci

4. In vivo development of teicoplanin resistance in a VanB Enterococcus faecium isolate;Hayden M. K.;J. Infect. Dis.,1993

5. Multiplex PCR detection of vanA, vanB, vanC-1, and vanC-2/3 genes in enterococci

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