Experimental Bacteriophage Protection against Staphylococcus aureus Abscesses in a Rabbit Model-Reference-Cited by-同舟云学术

Experimental Bacteriophage Protection against Staphylococcus aureus Abscesses in a Rabbit Model

Published:2005-03 Issue:3 Volume:49 Page:1220-1221
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Wills Quintin F.¹,Kerrigan Claire¹,Soothill James S.¹

Affiliation:

1. Infectious Diseases and Microbiology Unit, Institute of Child Health, University College London, London, United Kingdom

Abstract

ABSTRACT In a rabbit model of wound infection caused by Staphylococcus aureus , 2 × 10 9 PFU of staphylococcal phage prevented abscess formation in rabbits when it was injected simultaneously with S . aureus (8 × 10 7 CFU) into the same subcutaneous site. Phage multiplied in the tissues. Phages might be a valuable prophylaxis against staphylococcal infection.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.49.3.1220-1221.2005

Reference15 articles.

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