Liposome immunoassay for rapid identification of group A streptococci directly from throat swabs

Author:

Gerber M A1,Randolph M F1,DeMeo K K1

Affiliation:

1. Department of Pediatrics, University of Connecticut Health Center, Farmington 06032.

Abstract

The Q Test Strep (Becton Dickinson and Co., Franklin Lakes, N.J.) is a new solid-phase liposome immunoassay for the rapid diagnosis of group A beta-hemolytic streptococcal pharyngitis. Compared with blood agar plate cultures, the Q Test Strep had a sensitivity of 91%, a specificity of 83%, a positive predictive value of 88%, and a negative predictive value of 87%. Liposome technology can be used to facilitate the rapid diagnosis of group A beta-hemolytic streptococcal pharyngitis.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Reference8 articles.

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2. Evaluation of an ELISA for group A streptococcal antigen for diagnosis of pharyngitis;Dobkin D.;J. Pediatr.,1987

3. Specificity study of kits for detection of group A streptococci directly from throat swabs;Facklam R. R.;J. Clin. Microbiol.,1987

4. Gerber M. A. 1984. Diagnosis of pharyngitis: methodology of throat culture p. 61-72. In S. T. Shulman (ed.) Pharyngitis: management in an era of declining rheumatic fever. Praeger Publishers New York.

5. Comparison of throat cultures and rapid strep tests for diagnosis of streptococcal pharyngitis;Gerber M. A.;Pediatr. Infect. Dis. J.,1989

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