In Vitro Identification and In Vivo Confirmation of Inhibitors for Sweet Potato Chlorotic Stunt Virus RNA Silencing Suppressor, a Viral RNase III-Reference-Cited by-同舟云学术

In Vitro Identification and In Vivo Confirmation of Inhibitors for Sweet Potato Chlorotic Stunt Virus RNA Silencing Suppressor, a Viral RNase III

Published:2021-05-24 Issue:12 Volume:95 Page:
ISSN:0022-538X
Container-title:Journal of Virology
language:en
Short-container-title:J Virol

Author:

Wang Linping¹^ORCID,Poque Sylvain¹,Laamanen Karoliina²,Saarela Jani²,Poso Antti³⁴,Laitinen Tuomo³,Valkonen Jari P. T.¹

Affiliation:

1. Department of Agricultural Sciences, University of Helsinki, Helsinki, Finland

2. Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland

3. School of Pharmacy, University of Eastern Finland, Kuopio, Finland

4. Department of Internal Medicine VIII, University Hospital Tübingen, Tübingen, Germany

Abstract

We report here a high-throughput inhibitor identification method that targets a severe sweet potato virus disease caused by coinfection with two viruses (SPCSV and SPFMV). The disease is responsible for up to 90% yield losses.

Funder

China Scholarship Council

Bill and Melinda Gates Foundation

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/JVI.00107-21

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