Limited Utility of Procalcitonin in Identifying Community-Associated Bacterial Infections in Patients Presenting with Coronavirus Disease 2019-Reference-Cited by-同舟云学术

Limited Utility of Procalcitonin in Identifying Community-Associated Bacterial Infections in Patients Presenting with Coronavirus Disease 2019

Published:2021-03-18 Issue:4 Volume:65 Page:
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

May Michael¹^ORCID,Chang Michelle¹,Dietz Donald²,Shoucri Sherif²,Laracy Justin²,Sobieszczyk Magdalena E.²,Uhlemann Anne-Catrin²^ORCID,Zucker Jason²,Kubin Christine J.²^ORCID

Affiliation:

1. Department of Medicine, Columbia University Irving Medical Center, New York, New York, USA

2. Department of Medicine, Division of Infectious Diseases, Columbia University Irving Medical Center, New York, New York, USA

Abstract

The role of procalcitonin in identifying community-associated bacterial infections among patients with coronavirus disease 2019 is not yet established. In 2,443 patients with 148 bacterial coinfections, mean procalcitonin levels were significantly higher with any bacterial infection (13.16 ± 51.19 ng/ml; P = 0.0091) and with bacteremia (34.25 ± 85.01 ng/ml; P = 0.0125) than without infection (2.00 ± 15.26 ng/ml).

Funder

HHS | NIH | National Institute of Allergy and Infectious Diseases

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.02167-20

Reference16 articles.

1. Procalcitonin as a Biomarker in Respiratory Tract Infection

2. Procalcitonin as a Marker of Etiology in Adults Hospitalized With Community-Acquired Pneumonia

3. Procalcitonin as a diagnostic test for sepsis in critically ill adults and after surgery or trauma: A systematic review and meta-analysis