Responses of Mycobacterium tuberculosis to Growth in the Mouse Lung-Reference-Cited by-同舟云学术

Responses of Mycobacterium tuberculosis to Growth in the Mouse Lung

Published:2005-06 Issue:6 Volume:73 Page:3754-3757
ISSN:0019-9567
Container-title:Infection and Immunity
language:en
Short-container-title:Infect Immun

Author:

Dubnau Eugenie¹,Chan John²,Mohan V. P.²,Smith Issar¹

Affiliation:

1. TB Center, The Public Health Research Institute, 225 Warren Street Newark, New Jersey 07103

2. Montefiore Medical Center, Bronx, New York 10467

Abstract

ABSTRACT Using a promoter trap, we have identified 56 Mycobacterium tuberculosis genes preferentially expressed in the mouse lung. Quantitative real-time PCR showed that RNA levels of several genes were higher from bacteria growing in mouse lungs than from broth cultures. These results support the current hypothesis that Mycobacterium tuberculosis utilizes fatty acids as a carbon source in the mouse lung.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

Link

https://journals.asm.org/doi/pdf/10.1128/IAI.73.6.3754-3757.2005

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