Multicenter Antimicrobial Susceptibility Survey of Gram-Negative Bacteria Isolated from Patients with Community-Acquired Infections in the People's Republic of China

Author:

Ling Thomas K. W.1,Xiong Jianhui2,Yu Yunsong3,Lee Ching Ching1,Ye Huifen4,Hawkey Peter M.2

Affiliation:

1. Department of Microbiology, The Prince of Wales Hospital and The Chinese University of Hong Kong, Hong Kong

2. Division of Immunity and Infection, University of Birmingham, Birmingham, United Kingdom

3. Department of Infectious Diseases, The First Affiliated Hospital of Zhejiang University, Zhejiang, People's Republic of China

4. Microbiology, The First Municipal People's Hospital of Guangzhou, Guangzhou, People's Republic of China

Abstract

ABSTRACT A survey of 2,099 gram-negative bacilli from community infections at seven centers in the People's Republic of China is reported. The rates of resistance of 1,615 isolates of the family Enterobacteriaceae were as follows: 40.8% for ciprofloxacin, 32.2% for gentamicin, 0% for imipenem or ertapenem, and 14.7% for cefotaxime. The rates of extended-spectrum β-lactamase production were 16% for Escherichia coli and 17% for Klebsiella .

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Reference13 articles.

1. Bell, J., and J. Turnidge. 2003. SENTRY Antimicrobial Surveillance Program Asia-Pacific region and South Africa. Commun. Dis. Intell.27(Suppl.):S61-S66.

2. Three Cefotaximases, CTX-M-9, CTX-M-13, and CTX-M-14, among Enterobacteriaceae in the People's Republic of China

3. Chen, M. J., H. Wang, and China Nosocomial Pathogens Resistance Surveillance Study Group. 2003. Continuous surveillance of antimicrobial resistance among nosocomial gram-negative bacilli from intensive care unit in China. Zhonghua YiXue Za Zhi83:375-381. (In Chinese.)

4. In Vitro Activities of Ertapenem (MK-0826) against Clinical Bacterial Isolates from 11 North American Medical Centers

5. Hirakata, Y., J. Matsuda, Y. Miyazaki, S. Kamihira, S. Kawakami, Y. Miyazawa, Y. Ono, N. Nakazaki, Y. Hirata, M. Inoue, J. D. Turnidge, J. M. Bell, R. N. Jones, S. Kohno, and the SENTRY Asia-Pacific Participants. 2005. Regional variation in the prevalence of extended-spectrum beta-lactamase-producing clinical isolates in the Asia-Pacific region (SENTRY 1998-2002). Diagn. Microbiol. Infect. Dis.52:323-329.

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