In Vitro Activity of Beauvericin against All Developmental Stages of Sarcoptes scabiei-Reference-Cited by-同舟云学术

In Vitro Activity of Beauvericin against All Developmental Stages of Sarcoptes scabiei

Published:2020-04-21 Issue:5 Volume:64 Page:
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Al Khoury Charbel¹²,Nemer Nabil¹,Nemer Georges³,Kurban Mazen³⁴,Bernigaud Charlotte²⁵,Fischer Katja⁶,Guillot Jacques²

Affiliation:

1. Faculty of Agricultural and Food Sciences, Holy Spirit University of Kaslik, Jounieh, Lebanon

2. Research Group Dynamyc, EA7380, Université Paris-Est Créteil, Ecole Nationale Vétérinaire d’Alfort, USC ANSES, Maisons-Alfort, France

3. Department of Biochemistry and Molecular Genetics, American University of Beirut, Beirut, Lebanon

4. Department of Dermatology, American University of Beirut, Beirut, Lebanon

5. Department of Dermatology, Faculté de Médecine Paris-Est Créteil, AP-HP, Henri Mondor Hospital, Créteil, France

6. Scabies Laboratory, QIMR Berghofer Medical Research Institute, Infectious Diseases Program, Brisbane, Australia

Abstract

Scabies is a frequent cutaneous infection caused by the mite Sarcoptes scabiei in a large number of mammals, including humans. As the resistance of S. scabiei against several chemical acaricides has been previously documented, the establishment of alternative and effective control molecules is required. In this study, the potential acaricidal activity of beauvericin was assessed against different life stages of S. scabiei var. suis and in comparison with dimpylate and ivermectin, two commercially available molecules used for the treatment of S. scabiei infection in animals and/or humans.

Funder

Campus France / CEDRE

Centre National de la Recherche Scientifique

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.02118-19

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