Distribution of Endogenous Retroviruses in Crocodilians

Author:

Jaratlerdsiri Weerachai1,Rodríguez-Zárate Clara J.1,Isberg Sally R.12,Damayanti Chandramaya Siska1,Miles Lee G.1,Chansue Nantarika3,Moran Chris1,Melville Lorna4,Gongora Jaime1

Affiliation:

1. Centre for Advanced Technologies in Animal Genetics and Reproduction, Faculty of Veterinary Science, RMC Gunn Building, University of Sydney, Sydney, New South Wales 2006, Australia

2. Porosus Pty. Ltd., P.O. Box 86, Palmerston, Northern Territory 0831, Australia

3. Faculty of Veterinary Science, Chulalongkorn University, Pathumwan, Bangkok, 10330, Thailand

4. OIC Berrimah Veterinary Laboratories, Department of Primary Industry, Fisheries and Mines, GPO Box 3000 Darwin, Northern Territory 0801, Australia

Abstract

ABSTRACT Knowledge of endogenous retroviruses (ERVs) in crocodilians (Crocodylia) is limited, and their distribution among extant species is unclear. Here we analyzed the phylogenetic relationships of these retroelements in 20 species of crocodilians by studying the pro-pol gene. The results showed that crocodilian ERVs (CERVs) cluster into two major clades (CERV 1 and CERV 2). CERV 1 clustered as a sister group of the genus Gammaretrovirus , while CERV 2 clustered distantly with respect to all known ERVs. Interestingly, CERV 1 was found only in crocodiles (Crocodylidae). The data generated here could assist future studies aimed at identifying orthologous and paralogous ERVs among crocodilians.

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

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