Affiliation:
1. Department of Bacteriology, University of Wisconsin, Madison, Wisconsin
Abstract
Differences in the ability to withstand freeze-drying were demonstrated among strains of
Salmonella typhimurium
. On the average, the number of viable cells in freeze-dried cultures stored at 5 C for 12 to 18 months was approximately one half as large as that found 24 hr after freeze-drying. The viability in samples stored at higher temperatures declined rapidly and was correlated with the dryness of the sample. The virulence for mice of three strains of
S. typhimurium
did not change appreciably when samples were kept for 1 or 2 years as freeze-dried samples stored at 5 C, or as agar cultures stored at 5 C or at room temperature.
Publisher
American Society for Microbiology
Subject
General Pharmacology, Toxicology and Pharmaceutics,General Immunology and Microbiology,General Biochemistry, Genetics and Molecular Biology,General Medicine
Reference17 articles.
1. Procedure and apparatus for preservation in "lyophile;FLOSDORF E. W.;J. Immunol.,1935
2. The survival of bacteria during and after drying;FRY R. M.;J. Hyg.,1951
3. Transduction of virulence within the species Salmonella typhimurium;FURNESS G.;J. Gen. Microbiol.,1956
4. HUTTON R. S. 1948. Factors influencing preservation of Brucella abortus by Iyophilization. Ph.D. Thesis University of Wisconsin Madison.
5. Some physical factors that influence the survival of Brucella abortus during freeze-drying;HUTTON R. S.;J. Bacteriol.,1951
Cited by
4 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献