PixR, a Novel Activator of Conjugative Transfer of IncX4 Resistance Plasmids, Mitigates the Fitness Cost of <i>mcr-1</i> Carriage in Escherichia coli-Reference-Cited by-同舟云学术

PixR, a Novel Activator of Conjugative Transfer of IncX4 Resistance Plasmids, Mitigates the Fitness Cost of mcr-1 Carriage in Escherichia coli

Published:2022-02-22 Issue:1 Volume:13 Page:
ISSN:2150-7511
Container-title:mBio
language:en
Short-container-title:mBio

Author:

Yi Lingxian¹²,Durand Romain³^ORCID,Grenier Frédéric³,Yang Jun¹²,Yu Kaiyang¹²,Burrus Vincent³^ORCID,Liu Jian-Hua¹²^ORCID

Affiliation:

1. College of Veterinary Medicine, National Risk Assessment Laboratory for Antimicrobial Resistance of Microorganisms in Animals, Guangdong Provincial Key Laboratory of Veterinary Pharmaceutics Development and Safety Evaluation, South China Agricultural University, Guangzhou, China

2. Guangdong Laboratory for Lingnan Modern Agriculture, Guangzhou, China

3. Département de biologie, Université de Sherbrooke, Sherbrooke, Québec, Canada

Abstract

The spread of clinically relevant antibiotic resistance genes is often linked to the dissemination of epidemic plasmids. However, the underlying molecular mechanisms contributing to the successful spread of epidemic plasmids remain unclear.

Funder

National Natural Science Foundation of China

The 111 project

The innovation team project of Guangdong University

Natural Science and Engineering Research council of Canada

Gouvernement du Canada | Canadian Institutes of Health Research

Laboratory of Lingnan Modern Agriculture Project

Publisher

American Society for Microbiology

Subject

Virology,Microbiology

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