Genetic Ablation of a Female-Specific Apetala 2 Transcription Factor Blocks Oocyst Shedding in Cryptosporidium parvum-Reference-Cited by-同舟云学术

Genetic Ablation of a Female-Specific Apetala 2 Transcription Factor Blocks Oocyst Shedding in Cryptosporidium parvum

Published:2023-04-25 Issue:2 Volume:14 Page:
ISSN:2150-7511
Container-title:mBio
language:en
Short-container-title:mBio

Author:

Tandel Jayesh¹²,Walzer Katelyn A.¹^ORCID,Byerly Jessica H.¹,Pinkston Brittain²,Beiting Daniel P.¹^ORCID,Striepen Boris¹²^ORCID

Affiliation:

1. Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA

2. Center for Tropical and Emerging Global Diseases, University of Georgia, Athens, Georgia, USA

Abstract

The parasite Cryptosporidium infects millions of people worldwide each year, leading to life-threatening diarrheal disease in young children and immunosuppressed individuals. There is no vaccine and only limited treatment.

Funder

HHS | NIH | National Institute of Allergy and Infectious Diseases

Publisher

American Society for Microbiology

Subject

Virology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/mbio.03261-22

Reference65 articles.

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4. Parasitic infections: Time to tackle cryptosporidiosis

5. Burden and aetiology of diarrhoeal disease in infants and young children in developing countries (the Global Enteric Multicenter Study, GEMS): a prospective, case-control study

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