Author:
Rosenberg Z F,Pedersen F S,Haseltine W A
Abstract
The genomes of several strains of feline leukemia virus (FeLV) were compared by two-dimensional polyacrylamide gel electrophoresis of the large RNase T1-resistant oligonucleotides of the 70S RNA. Differences between each strain of FeLV tested were detected by this method. We estimate that the degree of sequence identity between the viruses is: FeLV A (Glasgow-1) to FeLV B (Snyder-Theilen), 52%; FeLV A (Glasgow-1) to FeLV C(Sarma), 66%; FeLV B(Snyder-Theilen) to FeLV C (Sarma), 37%. The fingerprints of two independent isolates of FeLV strains of subgroup A (Glasgow-1 and Rickard) were detectably different. We conclude that the RNase T1 oligonucleotide fingerprint pattern provides a useful tool for identification of FeLV strains.
Publisher
American Society for Microbiology
Subject
Virology,Insect Science,Immunology,Microbiology
Reference16 articles.
1. The association of the feline leukemia virus with Iymphosarcoma and other disorders;Cotter S. M.;J. Am. Vet. Med. Assoc.,1975
2. Horizontally and vertically transmitted oncornaviruses of cats;Essex M.;Adv. Cancer Res.,1975
3. Horizontal transmission of feline leukemia virus under natural conditions in a feline leukemia cluster household;Essex M.;Int. J. Cancer,1977
4. Biology of feline leukemia virus in the natural environment;Hardy W. D.;Cancer Res.,1976
5. Horizontal transmission of feline leukemia virus;Hardy W. D.;Nature (London),1973
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