Specificity of Diphtheria Toxin Action on Heart and Muscle Tissues of Guinea Pigs

Author:

Bowman C. G.1,Imhoff J. G.1,Bonventre P. F.1

Affiliation:

1. Department of Microbiology, University of Cincinnati, College of Medicine, Cincinnati, Ohio 45219

Abstract

Heart and muscle tissues appear to be specific target organs for the in vivo inhibition of protein synthesis by diphtheria toxin.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

Reference8 articles.

1. Bennett I. L. Jr. 1965. General host responses to infection p. 307-325. In R. J. Dubos and J. G. Hirsch (ed.) Bacterial and mycotic infections of man. J. B. Lippincott Co. Philadelphia.

2. Studies on the mode of action of diphtheria toxin. I. Protein synthesis in guinea pig tissues;Bonventre P. F.;J. Exp. Med.,1966

3. Studies on the mode of action of diphtherna toxin. II. Protein synthesis in primary heart cell cultures;Bonventre P. F.;J. Exp. Med.,1967

4. Studies on the mode of action of diphtheria toxin. III. Effect on subcellular components of protein synthesis from the tissues of intoxicated guinea pigs and rats;Bowman C. G.;J. Exp. Med.,1970

5. Studies on the mode of action of diphtheria toxin. VII. Toxin stimulated hydrolysis of nicotinamide adenine dinucleotide in mammalian cell extracts;Gill D. M.;J. Exp. Med.,1969

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