Activity of Ceftolozane-Tazobactam against a Broad Spectrum of Recent Clinical Anaerobic Isolates-Reference-Cited by-同舟云学术

Activity of Ceftolozane-Tazobactam against a Broad Spectrum of Recent Clinical Anaerobic Isolates

Published:2013-11-25 Issue:2 Volume:58 Page:1218-1223
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob. Agents Chemother.

Author:

Snydman David R.,McDermott Laura A.,Jacobus Nilda V.

Abstract

ABSTRACTWe evaluatedin vitroactivity of ceftolozane-tazobactam (TOL-TAZ), formerly CXA-201, against recent clinical anaerobic isolates with emphasis on theBacteroides fragilisgroup. Ceftolozane-tazobactam showed good activity againstB. fragilisspecies and intermediate to limited activity against other species ofBacteroides. Ceftolozane-tazobactam showed very good activity againstPrevotellaspp.,Fusobacteriumspp., andPropionibacteriumspp., varying activities against Gram-positive cocci, and limited activity againstClostridiumspp.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Reference10 articles.

1. In vitro potency of CXA-101, a novel cephalosporin against Pseudomonas aeruginosa displaying various resistance phenotypes, including multidrug resistance;Bulik;Antimicrob. Agents Chemother.,2010

2. Activity of a new cephalosporin, CXA-101 (FR264205), against β-lactam-resistant Pseudomonas aeruginosa mutants selected in vitro and after antipseudomonal treatment of intensive care unit patients;Moya;Antimicrob. Agents Chemother.,2010

3. Antimicrobial activity of CXA-101, a novel cephalosporin tested in combination with tazobactam against Enterobacteriaceae, Pseudomonas aeruginosa, and Bacteroides fragilis strains having various resistance phenotypes;Sader;Antimicrob. Agents Chemother.,2011

4. In vitro activity of CXA-101 plus tazobactam (CXA-201) against CTX-M-14 and CTX-M-15-producing Escherichia coli and Klebsiella pneumoniae;Titelman;Diagn. Microbiol. Infect. Dis.,2011

Cited by 41 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Rationale and evidence for the use of new beta-lactam/beta-lactamase inhibitor combinations and cefiderocol in critically ill patients;Annals of Intensive Care;2023-07-18

2. A Real-world Multicenter Outpatient Experience of Ceftolozane/Tazobactam;Open Forum Infectious Diseases;2023-03-28

3. Anaerobic Cocci;Principles and Practice of Pediatric Infectious Diseases;2023

4. Anaerop Bakterilerin Tanımlanmasında Çeşitli Yöntemlerin Karşılaştırılması ve Antibiyotiklere Karşı Duyarlılıkların Araştırılması;Flora the Journal of Infectious Diseases and Clinical Microbiology;2022-09-12

5. Efficacy and In Vitro Activity of Novel Antibiotics for Infections With Carbapenem-Resistant Gram-Negative Pathogens;Frontiers in Cellular and Infection Microbiology;2022-05-20