TnCentral: a Prokaryotic Transposable Element Database and Web Portal for Transposon Analysis

Author:

Ross Karen1ORCID,Varani Alessandro M.2ORCID,Snesrud Erik3,Huang Hongzhan4,Alvarenga Danillo Oliveira2ORCID,Zhang Jian1,Wu Cathy4ORCID,McGann Patrick3ORCID,Chandler Mick5ORCID

Affiliation:

1. Protein Information Resource, Department of Biochemistry and Molecular and Cellular Biology, Georgetown University Medical Center, Washington, DC, USA

2. School of Agricultural and Veterinary Sciences, Universidade Estadual Paulista, Jaboticabal, Sao Paulo, Brazil

3. Multidrug-Resistant Organism Repository and Surveillance Network, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA

4. Protein Information Resource, Center for Bioinformatics and Computational Biology, University of Delaware, Newark, Delaware, USA

5. Department of Biochemistry and Molecular and Cellular Biology, Georgetown University Medical Center, Washington, DC, USA

Abstract

The ability of bacteria to undergo rapid evolution and adapt to changing environmental circumstances drives the public health crisis of multiple antibiotic resistance, as well as outbreaks of disease in economically important agricultural crops and animal husbandry. Prokaryotic transposable elements (TE) play a critical role in this.

Publisher

American Society for Microbiology

Subject

Virology,Microbiology

Reference55 articles.

1. The Epidemic of Antibiotic-Resistant Infections: A Call to Action for the Medical Community from the Infectious Diseases Society of America

2. O’Neill J. 2016. Tackling drug-resistant infections globally: final report and recommendations. Welcome Foundation HM Government UK, London, United Kingdom.

3. A Moveable Feast: An Introduction to Mobile DNA

4. Insertion Sequences

5. Everyman's Guide to Bacterial Insertion Sequences

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