The Herpes Simplex Virus 1 Protein ICP4 Acts as both an Activator and a Repressor of Host Genome Transcription during Infection-Reference-Cited by-同舟云学术

The Herpes Simplex Virus 1 Protein ICP4 Acts as both an Activator and a Repressor of Host Genome Transcription during Infection

Published:2021-09-24 Issue:10 Volume:41 Page:
ISSN:0270-7306
Container-title:Molecular and Cellular Biology
language:en
Short-container-title:Mol Cell Biol

Author:

Rivas Thomas¹^ORCID,Goodrich James A.¹,Kugel Jennifer F.¹^ORCID

Affiliation:

1. Department of Biochemistry, University of Colorado—Boulder, Boulder, Colorado, USA

Abstract

Infection by herpes simplex virus 1 (HSV-1) impacts nearly all steps of host cell gene expression. The regulatory mechanisms by which this occurs, and the interplay between host and viral factors, have yet to be fully elucidated.

Funder

HHS | NIH | National Institute of General Medical Sciences

Publisher

American Society for Microbiology

Subject

Cell Biology,Molecular Biology

Link

https://journals.asm.org/doi/pdf/10.1128/MCB.00171-21

Reference68 articles.

1. Regulation of herpes simplex virus gene expression

2. Components of the REST/CoREST/histone deacetylase repressor complex are disrupted, modified, and translocated in HSV-1-infected cells

3. The Herpes Simplex Virus ICP0 RING Finger Domain Inhibits IRF3- and IRF7-Mediated Activation of Interferon-Stimulated Genes

4. Activation of immediate-early, early, and late promoters by temperature-sensitive and wild-type forms of herpes simplex virus type 1 protein ICP4

5. Expression of Herpes Simplex Virus ICP0 Inhibits the Induction of Interferon-Stimulated Genes by Viral Infection

Cited by 13 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Models of Herpes Simplex Virus Latency;Viruses;2024-05-08

2. A Revision of Herpes Simplex Virus Type 1 Transcription: First, Repress; Then, Express;Microorganisms;2024-01-26

3. The HSV-1 ICP22 protein selectively impairs histone repositioning upon Pol II transcription downstream of genes;Nature Communications;2023-07-31

4. ICP4-Associated Activation of Rap1b Facilitates Herpes Simplex Virus Type I (HSV-1) Infection in Human Corneal Epithelial Cells;Viruses;2023-06-27

5. HSV-1 Infection Induces a Downstream Shift of Promoter-Proximal Pausing for Host Genes;Journal of Virology;2023-05-31