Distinct Mycoplasma pneumoniae Interactions with Sulfated and Sialylated Receptors-Reference-Cited by-同舟云学术

Distinct Mycoplasma pneumoniae Interactions with Sulfated and Sialylated Receptors

Published:2020-10-19 Issue:11 Volume:88 Page:
ISSN:0019-9567
Container-title:Infection and Immunity
language:en
Short-container-title:Infect Immun

Author:

Williams Caitlin R.¹,Chen Li²³⁴,Sheppard Edward S.¹,Chopra Pradeep⁵,Locklin Jason²³⁴,Boons Geert-Jan⁵,Krause Duncan C.¹^ORCID

Affiliation:

1. Department of Microbiology, University of Georgia, Athens, Georgia, USA

2. Department of Chemistry, University of Georgia, Athens, Georgia, USA

3. College of Engineering, University of Georgia, Athens, Georgia, USA

4. New Materials Institute, University of Georgia, Athens, Georgia, USA

5. Complex Carbohydrate Research Center, University of Georgia, Athens, Georgia, USA

Abstract

Mycoplasma pneumoniae is a cell wall-less bacterial pathogen of the conducting airways, causing bronchitis and atypical or “walking” pneumonia in humans. M. pneumoniae recognizes sialylated and sulfated oligosaccharide receptors to colonize the respiratory tract, but the contribution of the latter is particularly unclear. We used chamber slides coated with sulfatide (3- O -sulfogalactosylceramide) to provide a baseline for M. pneumoniae binding and gliding motility.

Funder

HHS | NIH | National Institute of Allergy and Infectious Diseases

HHS | NIH | National Institute of General Medical Sciences

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

Link

https://journals.asm.org/doi/pdf/10.1128/IAI.00392-20

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