Affiliation:
1. Department of Microbiology, School of Pharmacy, Kitasato University, Tokyo, Japan
Abstract
The twin-arginine translocation (Tat) system is involved in not only a wide array of cellular processes but also pathogenesis in many bacterial pathogens; thus, this system is expected to become a novel therapeutic target to treat infections. To the best of our knowledge, involvement of the Tat system has not been reported in the gut infection caused by
Citrobacter rodentium
. Here, we studied the role of Tat in
C. rodentium
gut infection, which resembles human infection with enterohemorrhagic
Escherichia coli
(EHEC) and enteropathogenic
E. coli
(EPEC).
Funder
MEXT | Japan Society for the Promotion of Science
Publisher
American Society for Microbiology
Subject
Infectious Diseases,Immunology,Microbiology,Parasitology
Cited by
4 articles.
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