Molecular Typing of “Candidatus Bartonella ancashi,” a New Human Pathogen Causing Verruga Peruana

Author:

Mullins Kristin E.12,Hang Jun3,Jiang Ju2,Leguia Mariana4,Kasper Matthew R.4,Maguiña Ciro5,Jarman Richard G.3,Blazes David L.12,Richards Allen L.12

Affiliation:

1. Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA

2. U.S. Naval Medical Research Center, Silver Spring, Maryland, USA

3. Walter Reed Army Institute of Research, Silver Spring, Maryland, USA

4. U.S. Naval Medical Research Unit No. 6, Lima, Peru

5. Universidad Peruana Cayetano Heredia, Lima, Peru

Abstract

ABSTRACT A recently described clinical isolate, “ Candidatus Bartonella ancashi,” was obtained from a blood sample of a patient presenting with verruga peruana in the Ancash region of Peru. This sample and a second isolate obtained 60 days later from the same patient were molecularly typed using multilocus sequence typing (MLST) and multispacer sequence typing (MST). The isolates were 100% indistinguishable from each other but phylogenetically distant from Bartonella bacilliformis and considerably divergent from other known Bartonella species, confirming their novelty.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

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