Aspergillus Test Profiles and Mortality in Critically Ill COVID-19 Patients-Reference-Cited by-同舟云学术

Aspergillus Test Profiles and Mortality in Critically Ill COVID-19 Patients

Published:2021-11-18 Issue:12 Volume:59 Page:
ISSN:0095-1137
Container-title:Journal of Clinical Microbiology
language:en
Short-container-title:J Clin Microbiol

Author:

Ergün Mehmet¹²^ORCID,Brüggemann Roger J. M.¹³^ORCID,Alanio Alexandre⁴⁵^ORCID,Dellière Sarah⁴⁵^ORCID,van Arkel Andreas⁶,Bentvelsen Robbert G.⁶⁷,Rijpstra Tom⁸,van der Sar-van der Brugge Simone⁹,Lagrou Katrien¹⁰¹¹,Janssen Nico A. F.¹¹²,Buil Jochem B.¹²^ORCID,van Dijk Karin¹³,Melchers Willem J. G.¹²,Reijers Monique H. E.¹¹⁴,Schouten Jeroen A.¹⁵¹⁶,Wauters Joost¹⁷,Cordey Alan¹⁸,Soni Shuchita¹⁸,White P. Lewis¹⁸^ORCID,van de Veerdonk Frank L.¹¹²,Verweij Paul E.¹²^ORCID

Affiliation:

1. Center of Expertise in Mycology Radboudumc/CWZ, Radboud University Medical Center, Nijmegen, The Netherlands

2. Department of Medical Microbiology, Radboud University Medical Center, Nijmegen, The Netherlands

3. Department of Pharmacy, Radboud University Medical Center, Nijmegen, The Netherlands

4. Mycology-Parasitology Department, Hôpital Saint-Louis, Assistance Publique Hôpitaux de Paris, Paris, France

5. Molecular Mycology Unit, CNRS UMR2000, National Reference Centre for Invasive Mycoses and Antifungals, Institut Pasteur, Université de Paris, Paris, France

6. Microvida Laboratory for Microbiology, Amphia Hospital, Breda, The Netherlands

7. Department of Medical Microbiology, Leiden University Medical Centre, Leiden, The Netherlands

8. Department of Intensive Care Medicine, Amphia Hospital, Breda, The Netherlands

9. Department of Pulmonology, Amphia Hospital, Breda, The Netherlands

10. Department of Microbiology, Immunology and Transplantation, University Hospitals Leuven, Leuven, Belgium

11. Department of Laboratory Medicine and National Reference Center for Mycosis, University Hospitals Leuven, Leuven, Belgium

12. Department of Internal Medicine, Radboud University Medical Center, Nijmegen, The Netherlands

13. Amsterdam UMC, Vrije Universiteit Amsterdam, Department of Medical Microbiology and Infection Control, Amsterdam Infection & Immunity Institute, Amsterdam, The Netherlands

14. Department of Pulmonology, Radboud University Medical Center, Nijmegen, The Netherlands

15. Department of Intensive Care Medicine, Radboud University Medical Center, Nijmegen, The Netherlands

16. Scientific Centre for Quality of Healthcare (IQ healthcare), Radboud Institute for Health Sciences, Radboud University Medical Center, Nijmegen, The Netherlands

17. Department of General Internal Medicine, Medical Intensive Care Unit, University Hospitals Leuven, Leuven, Belgium

18. Public Health Wales Mycology Reference Laboratory, University Hospital of Wales, Cardiff, United Kingdom

Abstract

The literature regarding COVID-19-associated pulmonary aspergillosis (CAPA) has shown conflicting observations, including survival of CAPA patients not receiving antifungal therapy and discrepancy between CAPA diagnosis and autopsy findings. To gain insight into the pathophysiology of CAPA, we performed a case-control study in which we compared Aspergillus test profiles in CAPA patients and controls in relation to intensive care unit (ICU) mortality.

Publisher

American Society for Microbiology

Subject

Microbiology (medical)

Link

https://journals.asm.org/doi/pdf/10.1128/JCM.01229-21

Reference23 articles.

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