MIC and Upper Limit of Wild-Type Distribution for 13 Antifungal Agents against a Trichophyton mentagrophytes-Trichophyton interdigitale Complex of Indian Origin-Reference-Cited by-同舟云学术

MIC and Upper Limit of Wild-Type Distribution for 13 Antifungal Agents against a Trichophyton mentagrophytes-Trichophyton interdigitale Complex of Indian Origin

Published:2020-03-24 Issue:4 Volume:64 Page:
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Shaw Dipika¹,Singh Shreya¹,Dogra Sunil²,Jayaraman Jyothi³,Bhat Ramesh³,Panda Saumya⁴,Chakrabarti Arunaloke¹,Anjum Nishat⁵,Chowdappa Aruna⁶,Nagamoti Mahantesh⁶,Varshney Umesh⁵,Vanam Hari Pankaj⁷,Savio Jayanthi⁸,Antony Meryl⁹,Rudramurthy Shivaprakash M.¹^ORCID

Affiliation:

1. Department of Medical Microbiology, Postgraduate Institute of Medical Education and Research, Chandigarh, India

2. Departments of Dermatology, Venereology, and Leprology, Postgraduate Institute of Medical Education and Research, Chandigarh, India

3. Department of Dermatology, Venereology and Leprosy, Father Muller Medical College, Mangalore, Karnataka, India

4. Department of Dermatology, KPC Medical College, Kolkata, West Bengal, India

5. Department of Microbiology, Government Medical College Haldwani, Nainital, Uttarakhand, India

6. Department of Microbiology, Jawaharlal Nehru Medical College, Belagavi, Karnataka, India

7. Department of Microbiology, Bhaskar Medical College & General Hospital, Haidarabad, Telangana, India

8. Department of Microbiology, St. John’s Medical College & Hospital, Bangalore, Karnataka, India

9. Department of Dermatology, St. John’s Medical College & Hospital, Bangalore, Karnataka, India

Abstract

Dermatophytosis due to the Trichophyton mentagrophytes-Trichophyton interdigitale complex is being increasingly reported across India. Reports of therapeutic failure have surfaced recently, but there are no clinical break points (CBP) or epidemiological cutoffs (ECVs) available to guide the treatment of dermatophytosis. In this study, a total of 498 isolates of the T. mentagrophytes -interdigitale complex were collected from six medical centers over a period of five years (2014 to 2018).

Funder

Indian Association of Dermatologist Venerologists and Leprologists

Indian Council of Medical Research

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.01964-19

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2. High terbinafine resistance in Trichophyton interdigitale isolates in Delhi, India harbouring mutations in the squalene epoxidase gene