Bruceantin, a potent amoebicide from a plant, Brucea antidysenterica-Reference-Cited by-同舟云学术

Bruceantin, a potent amoebicide from a plant, Brucea antidysenterica

Published:1982-08 Issue:2 Volume:22 Page:342-345
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Gillin F D,Reiner D S,Suffness M

Abstract

Bruceantin, purified from an Ethiopian plant used to treat dysentery, killed Entamoeba histolytica in vitro (IC50 [the concentration of drug which decreased the number of colonies to half that of controls] = 0.018 microgram/ml). Six related quassinoids of 17 tested were also amoebicidal. No relationship between quassinoid structure and amoebicidal activity was apparent.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.22.2.342

Reference16 articles.

1. Action of antibiotics against intestinal amebae in vitro;Balamuth W.;Ann. N. Y. Acad. Sci.,1952

2. Cassady J. M. and M. Suffness. 1980. Terpenoid antitumor agents p. 201-269. In J. M. Cassady and J. D. Douros (ed.) Anticancer agents based on natural product models. Academic Press Inc. New York.

3. Un potente antiamebico d'origine vegetale: l'ailantone, principio attivo di Ailanthus glandulosa;De Carneri I.;Parassitologia (Rome),1968

4. Clinical trial of glaucarubin in treatment of amebiasis;Del Pozo E. C.;Am. J. Med.,1956

5. Axenic cultures for in vitro testing of drugs against Entamoeba histolytica;Diamond L. S.;Arch. Invest. Med.,1971

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