ApoA1 Neutralizes Proinflammatory Effects of Dengue Virus NS1 Protein and Modulates Viral Immune Evasion-Reference-Cited by-同舟云学术

ApoA1 Neutralizes Proinflammatory Effects of Dengue Virus NS1 Protein and Modulates Viral Immune Evasion

Published:2021-06-10 Issue:13 Volume:95 Page:
ISSN:0022-538X
Container-title:Journal of Virology
language:en
Short-container-title:J Virol

Author:

Coelho Diego R.¹²,Carneiro Pedro H.¹,Mendes-Monteiro Lucas¹,Conde Jonas N.³,Andrade Iamara⁴,Cao Thu⁵,Allonso Diego⁶,White-Dibiasio Michael⁷,Kuhn Richard J.⁵,Mohana-Borges Ronaldo¹^ORCID

Affiliation:

1. Laboratório de Biotecnologia e Bioengenharia Estrutural, Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Rio de Janeiro, Brazil

2. Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA

3. Department of Microbiology and Immunology, Stony Brook University, Stony Brook, New York, USA

4. Faculdade de Educação Tecnológica do Estado do Rio de Janeiro, Paracambi, Rio de Janeiro, Brazil

5. Department of Biological Sciences, Purdue University, West Lafayette, Indiana, USA

6. Departamento de Biotecnologia Farmacêutica, Faculdade de Farmácia, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Rio de Janeiro, Brazil

7. Affinia Therapeutics Inc., Waltham, Massachusetts, USA

Abstract

DENV is one of the most relevant mosquito-transmitted viruses worldwide, infecting more than 390 million people every year and leading to more than 20 thousand deaths. Although a DENV vaccine has already been approved, its potential side effects have hampered its use in large-scale immunizations.

Funder

Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro

MCTI | Conselho Nacional de Desenvolvimento Científico e Tecnológico

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/JVI.01974-20

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