Susceptibility to Infectious Diseases Based on Antimicrobial Peptide Production

Author:

Rivas-Santiago Bruno1,Serrano Carmen J.1,Enciso-Moreno J. Antonio1

Affiliation:

1. Unidad de Investigación Médica Zacatecas, Instituto Mexicano del Seguro Social (IMSS), Zacatecas City, Mexico

Abstract

ABSTRACT In the last few years, the great impact of antimicrobial peptides on infectious disease susceptibility and natural resistance has been reported. In some cases, susceptibility to diseases is related to antimicrobial peptide polymorphisms and gene copy numbers, but for the vast majority of infectious diseases, these phenomena need to be elucidated. This review is focused on the current knowledge about susceptibility and resistance conferred by genetic variations in antimicrobial peptide expression in infectious diseases.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Immunology,Microbiology,Parasitology

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