Affiliation:
1. Unidad de Investigación Médica Zacatecas, Instituto Mexicano del Seguro Social (IMSS), Zacatecas City, Mexico
Abstract
ABSTRACT
In the last few years, the great impact of antimicrobial peptides on infectious disease susceptibility and natural resistance has been reported. In some cases, susceptibility to diseases is related to antimicrobial peptide polymorphisms and gene copy numbers, but for the vast majority of infectious diseases, these phenomena need to be elucidated. This review is focused on the current knowledge about susceptibility and resistance conferred by genetic variations in antimicrobial peptide expression in infectious diseases.
Publisher
American Society for Microbiology
Subject
Infectious Diseases,Immunology,Microbiology,Parasitology
Reference80 articles.
1. Abiko, Y., and M. Saitoh. 2007. Salivary defensins and their importance in oral health and disease. Curr. Pharm. Des.13:3065-3072.
2. Impaired Expression of Perforin and Granulysin in CD8
+
T Cells at the Site of Infection in Human Chronic Pulmonary Tuberculosis
3. Araujo, Z., M. Acosta, H. Escobar, R. Banos, C. Fernandez de Larrea, and B. Rivas-Santiago. 2008. Immunitary response in tuberculosis and the role of Mycobacterium tuberculosis secretion antigens in its protection, pathology and diagnosis: review. Invest. Clin.49:411-441. (In Spanish.)
4. Bals, R., X. Wang, Z. Wu, T. Freeman, V. Bafna, M. Zasloff, and J. M. Wilson. 1998. Human beta-defensin 2 is a salt-sensitive peptide antibiotic expressed in human lung. J. Clin. Investig.102:874-880.
5. Bals, R., and J. M. Wilson. 2003. Cathelicidins—a family of multifunctional antimicrobial peptides. Cell. Mol. Life Sci.60:711-720.
Cited by
76 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献