Affiliation:
1. Rockefeller University, New York, New York 10021-6399.
Abstract
A beta-lactam-resistant serotype 23F Streptococcus pneumoniae clinical isolate from the cerebrospinal fluid of a pediatric patient from California is unusual in that the MICs of cefotaxime and ceftriaxone (2.5 micrograms/ml each) are higher than that of benzylpenicillin (0.3 micrograms/ml); the isolate also has patterns of penicillin-binding proteins and of cell wall peptides which are atypical compared with those of previously examined penicillin-resistant pneumococci.
Publisher
American Society for Microbiology
Subject
Infectious Diseases,Pharmacology (medical),Pharmacology
Reference10 articles.
1. Ceftriaxone failure in meningitis caused by Streptococcus pneumoniae with reduced susceptibility to beta-lactam antibiotics;Bradley J. S.;Pediatr. Infect. Dis. J.,1991
2. Serotype distribution and antimicrobial resistance of Streptococcus pneumoniae isolates producing systemic infections in Spain, 1979-1988;Fenoll A.;Rev. Clin. Microbiol.,1990
3. A biological price of antibiotic resistance: major changes in the peptidoglycan structure of penicillin resistant pneumococci;Garcia-Bustos J.;Proc. Natl. Acad. Sci. USA,1990
4. Penicillin binding protein families: evidence for the clonal nature of penicillin resistance in clinical isolates of pneumococci;Jabes D.;J. Infect. Dis.,1988
5. Antimicrobial susceptibility testing of pneumococci. 2. Determination of optimal disc diffusion test for the detection of penicillin G resistance;Jacobs M. R.;J. Antimicrob. Chemother.,1980
Cited by
102 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献