A pneumococcal clinical isolate with high-level resistance to cefotaxime and ceftriaxone

Author:

Figueiredo A M1,Connor J D1,Severin A1,Vaz Pato M V1,Tomasz A1

Affiliation:

1. Rockefeller University, New York, New York 10021-6399.

Abstract

A beta-lactam-resistant serotype 23F Streptococcus pneumoniae clinical isolate from the cerebrospinal fluid of a pediatric patient from California is unusual in that the MICs of cefotaxime and ceftriaxone (2.5 micrograms/ml each) are higher than that of benzylpenicillin (0.3 micrograms/ml); the isolate also has patterns of penicillin-binding proteins and of cell wall peptides which are atypical compared with those of previously examined penicillin-resistant pneumococci.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Reference10 articles.

1. Ceftriaxone failure in meningitis caused by Streptococcus pneumoniae with reduced susceptibility to beta-lactam antibiotics;Bradley J. S.;Pediatr. Infect. Dis. J.,1991

2. Serotype distribution and antimicrobial resistance of Streptococcus pneumoniae isolates producing systemic infections in Spain, 1979-1988;Fenoll A.;Rev. Clin. Microbiol.,1990

3. A biological price of antibiotic resistance: major changes in the peptidoglycan structure of penicillin resistant pneumococci;Garcia-Bustos J.;Proc. Natl. Acad. Sci. USA,1990

4. Penicillin binding protein families: evidence for the clonal nature of penicillin resistance in clinical isolates of pneumococci;Jabes D.;J. Infect. Dis.,1988

5. Antimicrobial susceptibility testing of pneumococci. 2. Determination of optimal disc diffusion test for the detection of penicillin G resistance;Jacobs M. R.;J. Antimicrob. Chemother.,1980

Cited by 102 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Streptococcus pneumoniae;Principles and Practice of Pediatric Infectious Diseases;2023

2. Streptococcus pneumoniae;Principles and Practice of Pediatric Infectious Diseases;2018

3. Impact of Penicillin Nonsusceptibility on Clinical Outcomes of Patients with Nonmeningeal Streptococcus pneumoniae Bacteremia in the Era of the 2008 Clinical and Laboratory Standards Institute Penicillin Breakpoints;Antimicrobial Agents and Chemotherapy;2012-06-11

4. Streptococcus pneumoniae;Principles and Practice of Pediatric Infectious Diseases;2012

5. Ten-year surveillance of invasive Streptococcus pneumoniae isolates in central Turkey prior to the introduction of a conjugate vaccine;The Journal of Infection in Developing Countries;2010-05-04

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3