Antibiotic Susceptibility of Clinical Burkholderia pseudomallei Isolates in Northeast Thailand from 2015 to 2018 and the Genomic Characterization of β -Lactam-Resistant Isolates-Reference-Cited by-同舟云学术

Antibiotic Susceptibility of Clinical Burkholderia pseudomallei Isolates in Northeast Thailand from 2015 to 2018 and the Genomic Characterization of β -Lactam-Resistant Isolates

Published:2021-04-19 Issue:5 Volume:65 Page:
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Hii Shirley Yi Fen¹,Tandhavanant Sarunporn¹,Phunpang Rungnapa²,Ekchariyawat Peeraya¹³,Saiprom Natnaree¹,Chewapreecha Claire²⁴⁵,Seng Rathanin¹,Thiansukhon Ekkachai⁶,Morakot Chumpol⁷,Sangsa Narongchai⁸,Chayangsu Sunee⁹,Chuananont Somchai¹⁰,Tanwisaid Kittisak¹⁰,Silakun Wirayut¹¹,Buasi Noppol¹²,Chaisuksant Seksan¹³,Hompleum Tanin¹⁴,Chetchotisakd Ploenchan¹⁵,Day Nicholas P. J.²¹⁶,Chantratita Wasun¹⁷,Lertmemongkolchai Ganjana¹⁸¹⁹^ORCID,West T. Eoin²⁰,Chantratita Narisara¹²^ORCID

Affiliation:

1. Department of Microbiology and Immunology, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand

2. Mahidol-Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand

3. Department of Microbiology, Faculty of Public Health, Mahidol University, Bangkok, Thailand

4. Wellcome Sanger Institute, Hinxton, United Kingdom

5. Bioinformatics and Systems Biology Program, School of Bioresource and Technology, King Mongkut’s University of Technology Thonburi, Bangkok, Thailand

6. Department of Medicine, Udon Thani Hospital, Udon Thani, Thailand

7. Department of Medicine, Mukdahan Hospital, Mukdahan, Thailand

8. Department of Medicine, Roi Et Hospital, Roi Et, Thailand

9. Department of Medicine, Surin Hospital, Surin, Thailand

10. Department of Medicine, Nakhon Phanom Hospital, Nakhon Phanom, Thailand

11. Department of Medicine, Buriram Hospital, Buriram, Thailand

12. Department of Medicine, Sisaket Hospital, Sisaket, Thailand

13. Department of Medicine, Khon Kaen Hospital, Khon Kaen, Thailand

14. Department of Surgery, Khon Kaen Hospital, Khon Kaen, Thailand

15. Department of Medicine, Srinagarind Hospital, Faculty of Medicine and Research and Diagnostic Center for Emerging Infectious Diseases (RCEID), Khon Kaen University, Khon Kaen, Thailand

16. Center for Tropical Medicine and Global Health, University of Oxford, United Kingdom

17. Center for Medical Genomics, Faculty of Medicine, Ramathibodi Hospital, Bangkok, Thailand

18. Department of Clinical Immunology, Faculty of Associated Medical Science, Khon Kaen University, Khon Kaen, Thailand

19. The Centre for Research and Development of Medical Diagnostic Laboratories, Khon Kaen University, Khon Kaen, Thailand

20. Division of Pulmonary, Critical Care & Sleep Medicine, Harborview Medical Center, University of Washington, Seattle, Washington, USA

Abstract

Melioidosis is an often fatal infection in tropical regions caused by an environmental bacterium, Burkholderia pseudomallei . Current recommended melioidosis treatment requires intravenous β-lactam antibiotics such as ceftazidime (CAZ), meropenem (MEM), or amoxicillin-clavulanic acid (AMC) and oral trimethoprim-sulfamethoxazole.

Funder

Wellcome Trust

Thailand Research Fund

Deutscher Akademischer Austauschdienst

HHS | NIH | National Institute of Allergy and Infectious Diseases

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.02230-20

Reference51 articles.