Activities of New Fluoroquinolones, Ketolides, and Other Antimicrobials against Blood Culture Isolates of Viridans Group Streptococci from across Canada, 2000

Author:

Gershon Andrea S.1,de Azavedo Joyce C. S.12,McGeer Allison12,Ostrowska Krystyna I.3,Church Deirdre4,Hoban Daryl J.5,Harding Godfrey K. M.6,Weiss Karl7,Abbott Lewis8,Smaill Fiona9,Gourdeau Marie10,Murray Gilles10,Low Donald E.23

Affiliation:

1. University of Toronto

2. Toronto Medical Laboratories and Mount Sinai Hospital, Toronto

3. Trillium Health Centre, Mississauga

4. Calgary Laboratory Services, Calgary, Alberta

5. Health Sciences Centre

6. St. Boniface General Hospital, Winnipeg, Manitoba

7. Hopital Maisonneuve-Rosemont, University of Montreal, Montreal

8. Queen Elizabeth Hospital, Charlottetown, Prince Edward Island, Canada

9. Hamilton Health Sciences Centre, Hamilton, Ontario

10. Hopital de l'Enfant-Jesus, Quebec City, Quebec

Abstract

ABSTRACT The rates of nonsusceptibility to penicillin, erythromycin, and clindamycin of 191 blood culture isolates of viridans group streptococci collected from across Canada in 2000 were 36, 42, and 10%, respectively. Although 8% of the strains were resistant to ciprofloxacin (MIC ⩾ 4 μg/ml), the MICs of gemifloxacin, BMS 284756, telithromycin, and ABT 773 at which 90% of the strains were inhibited were 0.06, 0.06, 0.12, and 0.03 μg/ml, respectively.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

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