In Vitro and In Vivo Activities of TP0480066, a Novel Topoisomerase Inhibitor, against Neisseria gonorrhoeae-Reference-Cited by-同舟云学术

In Vitro and In Vivo Activities of TP0480066, a Novel Topoisomerase Inhibitor, against Neisseria gonorrhoeae

Published:2021-03-18 Issue:4 Volume:65 Page:
ISSN:0066-4804
Container-title:Antimicrobial Agents and Chemotherapy
language:en
Short-container-title:Antimicrob Agents Chemother

Author:

Masuko Aiko¹,Takata Iichiro¹,Fujita Kiyoko¹,Okumura Hirotoshi²,Ushiyama Fumihito³^ORCID,Amada Hideaki³,Sugiyama Hiroyuki¹^ORCID

Affiliation:

1. Pharmacology Laboratories, Taisho Pharmaceutical Co., Ltd., Saitama, Japan

2. Drug Safety and Pharmacokinetics Laboratories, Taisho Pharmaceutical Co., Ltd., Saitama, Japan

3. Chemistry Laboratories, Taisho Pharmaceutical Co., Ltd., Saitama, Japan

Abstract

Gonorrhea is a common, sexually transmitted disease caused by Neisseria gonorrhoeae . Multidrug-resistant N. gonorrhoeae is an urgent threat, and the development of a new antimicrobial agent that functions via a new mechanism is strongly desired.

Publisher

American Society for Microbiology

Subject

Infectious Diseases,Pharmacology (medical),Pharmacology

Link

https://journals.asm.org/doi/pdf/10.1128/AAC.02145-20

Reference40 articles.

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